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Light-Activated Drug Treatment for Retina Vessels

Iowa rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated July 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$407

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $407 for this service. The price depends on where it is billed: about $363 from a physician practice, and about $2,291 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$363$275 to $537
FacilityA hospital or hospital-owned outpatient department$2,291$676 to $3,802

How much rates vary

Facilitymedian $2,291 · 10th to 90th $363 to $6,761Professionalmedian $363 · 10th to 90th $214 to $1,288
$100$200$500$1K$2K$5K$10Kfacility $2,291professional $363

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$363.08
Median
$3,388.44
Typical High
$7,943.28
Aetna
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$346.74
Typical High
$1,288.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$537.03
Typical High
$724.44
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$338.84
Typical High
$1,096.48
Medica
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$676.08
Typical High
$3,235.94
Medica
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$575.44
Typical High
$1,548.82
Midlands
Setting
Professional
Modifier
Global
Typical Low
$501.19
Median
$616.60
Typical High
$741.31
Midlands
Setting
Professional
Modifier
Global
Typical Low
$575.44
Median
$575.44
Typical High
$575.44
United
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$1,513.56
Typical High
$4,073.80
United
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$398.11
Typical High
$691.83
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$416.87
Typical High
$691.83

Where Iowa sits

The same service costs 3.8 times more in Wyoming than in West Virginia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 12th of 51

$407

WY $977WV $257

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.