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Light-Activated Drug Treatment for Retina Vessels

Mississippi rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated October 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$363

Typical negotiated rate. In Mississippi, October 2026.

Insurers have agreed to pay about $363 for this service. The price depends on where it is billed: about $324 from a physician practice, and about $501 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$324$263 to $513
FacilityA hospital or hospital-owned outpatient department$501$302 to $891

How much rates vary

Facilitymedian $501 · 10th to 90th $174 to $1,445Professionalmedian $324 · 10th to 90th $200 to $692
$200$500$1K$2Kfacility $501professional $324

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$758.58
Typical High
$1,819.70
Aetna
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$512.86
Typical High
$676.08
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$107.15
Median
$257.04
Typical High
$338.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$42.66
Median
$102.33
Typical High
$134.90
Aetna
Setting
Professional
Modifier
54 · Surgery only
Typical Low
$162.18
Median
$389.05
Typical High
$512.86
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$32.36
Median
$77.62
Typical High
$102.33
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$21.38
Median
$51.29
Typical High
$67.61
BCBS Mississippi
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
BCBS Mississippi
Setting
Professional
Modifier
None
Typical Low
$691.83
Median
$691.83
Typical High
$691.83
Cigna
Setting
Facility
Modifier
None
Typical Low
$154.88
Median
$190.55
Typical High
$524.81
Cigna
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$281.84
Typical High
$407.38
Molina
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$33.11
United
Setting
Facility
Modifier
None
Typical Low
$302.00
Median
$616.60
Typical High
$1,584.89
United
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$269.15
Typical High
$562.34

Where Mississippi sits

The same service costs 3.5 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 14th of 51

$363

AK $832FL $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.