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Light-Activated Drug Treatment for Retina Vessels

Mississippi rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated July 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$339

Typical negotiated rate. In Mississippi, July 2026.

Insurers have agreed to pay about $339 for this service. The price depends on where it is billed: about $295 from a physician practice, and about $776 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$295$224 to $513
FacilityA hospital or hospital-owned outpatient department$776$479 to $1,096

How much rates vary

Facilitymedian $776 · 10th to 90th $288 to $1,820Professionalmedian $295 · 10th to 90th $195 to $661
$50.0$100.0$200.0$500.0$1.0K$2.0K$5.0Kfacility $776professional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$524.81
Typical High
$1,819.70
Aetna
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$295.12
Typical High
$660.69
BCBS
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
BCBS
Setting
Professional
Modifier
Global
Typical Low
$691.83
Median
$691.83
Typical High
$691.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$173.78
Typical High
$776.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$302.00
Typical High
$524.81
Molina
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$32.36
Typical High
$33.11
United
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$954.99
Typical High
$1,819.70
United
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$281.84
Typical High
$562.34

Where Mississippi sits

The same service costs 3.8 times more in Wyoming than in West Virginia. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Mississippi $339 · 25th of 51
WY $977WV $257

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.