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Light-Activated Drug Treatment for Retina Vessels

Indiana rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated July 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$295

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $295 for this service. The price depends on where it is billed: about $257 from a physician practice, and about $4,074 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$257$209 to $302
FacilityA hospital or hospital-owned outpatient department$4,074$3,311 to $5,495

How much rates vary

Facilitymedian $4,074 · 10th to 90th $832 to $8,318Professionalmedian $257 · 10th to 90th $195 to $407
$100.0$200.0$500.0$1.0K$2.0K$5.0K$10.0Kfacility $4,074professional $257

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$3,801.89
Typical High
$5,623.41
Aetna
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$257.04
Typical High
$354.81
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,570.40
Median
$4,365.16
Typical High
$8,317.64
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$204.17
Typical High
$346.74
CareSource
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Cigna
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$354.81
Typical High
$446.68
Cigna
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$288.40
Typical High
$467.74
United
Setting
Facility
Modifier
Global
Typical Low
$416.87
Median
$2,691.53
Typical High
$4,265.80
United
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$288.40
Typical High
$467.74

Where Indiana sits

The same service costs 3.8 times more in Wyoming than in West Virginia. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Indiana $295 · 38th of 51
WY $977WV $257

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.