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Light-Activated Drug Treatment for Retina Vessels

Virginia rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated October 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$257

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $257 for this service. The price depends on where it is billed: about $245 from a physician practice, and about $1,230 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$245$209 to $309
FacilityA hospital or hospital-owned outpatient department$1,230$355 to $2,754

How much rates vary

Facilitymedian $1,230 · 10th to 90th $224 to $5,623Professionalmedian $245 · 10th to 90th $191 to $398
$200$500$1K$2K$5K$10Kfacility $1,230professional $245

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$4,786.30
Typical High
$14,125.38
Aetna
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$257.04
Typical High
$389.05
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$1,698.24
Median
$2,398.83
Typical High
$2,951.21
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$234.42
Typical High
$269.15
CareFirst
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$223.87
Typical High
$263.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$323.59
Typical High
$1,621.81
Cigna
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$263.03
Typical High
$380.19
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$275.42
Median
$323.59
Typical High
$398.11
Medcost
Setting
Professional
Modifier
None
Typical Low
$467.74
Median
$467.74
Typical High
$588.84
Medcost
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$269.15
Typical High
$512.86
Medcost
Setting
Professional
Modifier
None
Typical Low
$346.74
Median
$346.74
Typical High
$346.74
Sentara
Setting
Facility
Modifier
None
Typical Low
$204.17
Median
$616.60
Typical High
$2,951.21
Sentara
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$354.81
Typical High
$1,737.80
United
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$1,412.54
Typical High
$3,630.78
United
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$251.19
Typical High
$446.68
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$128.82
Typical High
$173.78
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$51.29
Typical High
$69.18
Aetna
Setting
Professional
Modifier
54 · Surgery only
Typical Low
$138.04
Median
$194.98
Typical High
$263.03
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$27.54
Median
$38.90
Typical High
$52.48
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$18.20
Median
$25.70
Typical High
$34.67

Where Virginia sits

The same service costs 3.5 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 47th of 51

$257

AK $832FL $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.