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Light-Activated Drug Treatment for Retina Vessels

South Dakota rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated July 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$372

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $372 for this service. The price depends on where it is billed: about $372 from a physician practice, and about $363 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$372$251 to $479
FacilityA hospital or hospital-owned outpatient department$363$251 to $794

How much rates vary

Facilitymedian $363 · 10th to 90th $195 to $4,365Professionalmedian $372 · 10th to 90th $186 to $661
$200.0$500.0$1.0K$2.0Kfacility $363professional $372

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$2,290.87
Typical High
$4,365.16
Aetna
Setting
Professional
Modifier
Global
Typical Low
$177.83
Median
$239.88
Typical High
$478.63
Cigna
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$602.56
Typical High
$831.76
Medica
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$338.84
Typical High
$741.31
Medica
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$501.19
Typical High
$1,548.82
Midlands
Setting
Professional
Modifier
Global
Typical Low
$501.19
Median
$660.69
Typical High
$676.08
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$407.38
Typical High
$537.03
United
Setting
Facility
Modifier
Global
Typical Low
$1,659.59
Median
$1,659.59
Typical High
$1,659.59
United
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$426.58
Typical High
$758.58
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$426.58
Typical High
$724.44

Where South Dakota sits

The same service costs 3.8 times more in Wyoming than in West Virginia. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $372 · 15th of 51
WY $977WV $257

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.