go back

Light-Activated Drug Treatment for Retina Vessels

Nebraska rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated October 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$380

Typical negotiated rate. In Nebraska, October 2026.

Insurers have agreed to pay about $380 for this service. The price depends on where it is billed: about $372 from a physician practice, and about $708 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$372$275 to $575
FacilityA hospital or hospital-owned outpatient department$708$347 to $3,236

How much rates vary

Facilitymedian $708 · 10th to 90th $251 to $6,310Professionalmedian $372 · 10th to 90th $195 to $1,549
$200$500$1K$2K$5K$10Kfacility $708professional $372

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$263.03
Median
$3,801.89
Typical High
$11,481.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$263.03
Typical High
$489.78
BCBS Nebraska
Setting
Facility
Modifier
None
Typical Low
$4,265.80
Median
$5,623.41
Typical High
$11,481.54
BCBS Nebraska
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$288.40
Typical High
$389.05
Cigna
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$275.42
Typical High
$323.59
Cigna
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$616.60
Typical High
$676.08
Medica
Setting
Facility
Modifier
None
Typical Low
$371.54
Median
$660.69
Typical High
$2,290.87
Medica
Setting
Professional
Modifier
None
Typical Low
$478.63
Median
$1,548.82
Typical High
$2,041.74
Midlands
Setting
Professional
Modifier
None
Typical Low
$501.19
Median
$660.69
Typical High
$724.44
Midlands
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$269.15
Typical High
$346.74
Midlands
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$645.65
Typical High
$724.44
United
Setting
Facility
Modifier
None
Typical Low
$467.74
Median
$741.31
Typical High
$2,754.23
United
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$501.19
Typical High
$691.83
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$97.72
Median
$131.83
Typical High
$181.97
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$38.90
Median
$52.48
Typical High
$74.13
Aetna
Setting
Professional
Modifier
54 · Surgery only
Typical Low
$144.54
Median
$194.98
Typical High
$275.42
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$28.84
Median
$39.81
Typical High
$54.95
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$19.50
Median
$26.30
Typical High
$36.31

Where Nebraska sits

The same service costs 3.5 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 11th of 51

$380

AK $832FL $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.