go back

Light-Activated Drug Treatment for Retina Vessels

California rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated July 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$525

Typical negotiated rate. In California, July 2026.

Insurers have agreed to pay about $525 for this service. The price depends on where it is billed: about $275 from a physician practice, and about $5,495 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 13 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$275$229 to $437
FacilityA hospital or hospital-owned outpatient department$5,495$3,715 to $8,318

How much rates vary

Facilitymedian $5,495 · 10th to 90th $1,318 to $13,490Professionalmedian $275 · 10th to 90th $186 to $1,122
$100.0$1.0K$10.0Kfacility $5,495professional $275

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$1,584.89
Median
$5,623.41
Typical High
$16,982.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$275.42
Typical High
$1,122.02
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$630.96
Median
$630.96
Typical High
$630.96
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,388.44
Median
$5,888.44
Typical High
$13,489.63
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$407.38
Typical High
$794.33
Blue Shield
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$3,019.95
Typical High
$6,456.54
Blue Shield
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$288.40
Typical High
$724.44
Cigna
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$295.12
Typical High
$549.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$331.13
Typical High
$691.83
Contra Costa Health
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$288.40
Typical High
$446.68
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$302.00
Typical High
$549.54
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$56.23
Typical High
$1,288.25
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$2,041.74
Median
$2,344.23
Typical High
$2,344.23
Molina
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$229.09
Typical High
$380.19
Providence
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$323.59
Typical High
$512.86
Providence
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$338.84
Typical High
$630.96
Sutter Health Plus
Setting
Professional
Modifier
Global
Typical Low
$691.83
Median
$691.83
Typical High
$933.25
The Alliance
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$380.19
Typical High
$549.54
United
Setting
Facility
Modifier
Global
Typical Low
$1,122.02
Median
$2,884.03
Typical High
$7,943.28
United
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$263.03
Typical High
$549.54

Where California sits

The same service costs 3.8 times more in Wyoming than in West Virginia. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

California $525 · 4th of 51
WY $977WV $257

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.