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Light-Activated Drug Treatment for Retina Vessels

Colorado rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated October 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$347

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $295 from a physician practice, and about $2,399 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$295$245 to $372
FacilityA hospital or hospital-owned outpatient department$2,399$1,047 to $3,548

How much rates vary

Facilitymedian $2,399 · 10th to 90th $398 to $5,129Professionalmedian $295 · 10th to 90th $219 to $479
$200$500$1K$2K$5K$10Kfacility $2,399professional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$954.99
Median
$3,311.31
Typical High
$8,709.64
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$269.15
Typical High
$398.11
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$2,137.96
Median
$3,311.31
Typical High
$5,370.32
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$295.12
Typical High
$501.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$331.13
Typical High
$1,659.59
Cigna
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$295.12
Typical High
$426.58
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$331.13
Typical High
$478.63
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$295.12
Typical High
$446.68
Select Health
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$295.12
Typical High
$616.60
Select Health
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$213.80
Typical High
$295.12
United
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$1,122.02
Typical High
$2,754.23
United
Setting
Professional
Modifier
None
Typical Low
$218.78
Median
$316.23
Typical High
$524.81
5 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$123.03
Median
$125.89
Typical High
$165.96
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$48.98
Median
$51.29
Typical High
$66.07
Aetna
Setting
Professional
Modifier
54 · Surgery only
Typical Low
$181.97
Median
$190.55
Typical High
$251.19
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$36.31
Median
$38.02
Typical High
$50.12
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$24.55
Median
$25.12
Typical High
$33.11

Where Colorado sits

The same service costs 3.5 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 21st of 51

$347

AK $832FL $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.