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Light-Activated Drug Treatment for Retina Vessels

Kentucky rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated October 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$251

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $251 for this service. The price depends on where it is billed: about $251 from a physician practice, and about $331 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$251$200 to $324
FacilityA hospital or hospital-owned outpatient department$331$224 to $759

How much rates vary

Facilitymedian $331 · 10th to 90th $191 to $2,239Professionalmedian $251 · 10th to 90th $174 to $417
$50$200$1K$5Kfacility $331professional $251

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$213.80
Median
$288.40
Typical High
$851.14
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$269.15
Typical High
$338.84
Ambetter
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$575.44
Median
$3,801.89
Typical High
$11,220.18
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$204.17
Typical High
$346.74
CareSource
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$204.17
Typical High
$302.00
CareSource
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$263.03
Typical High
$309.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$34.67
Median
$190.55
Typical High
$398.11
Cigna
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$257.04
Typical High
$2,041.74
Molina
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$33.11
United
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$588.84
Typical High
$1,621.81
United
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$251.19
Typical High
$398.11
10 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$107.15
Median
$144.54
Typical High
$190.55
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$42.66
Median
$57.54
Typical High
$77.62
Aetna
Setting
Facility
Modifier
54 · Surgery only
Typical Low
$162.18
Median
$213.80
Typical High
$288.40
Aetna
Setting
Facility
Modifier
55 · Aftercare only
Typical Low
$32.36
Median
$42.66
Typical High
$57.54
Aetna
Setting
Facility
Modifier
56 · Pre-op care only
Typical Low
$21.38
Median
$28.84
Typical High
$38.90
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$107.15
Median
$134.90
Typical High
$151.36
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$42.66
Median
$53.70
Typical High
$60.26
Aetna
Setting
Professional
Modifier
54 · Surgery only
Typical Low
$162.18
Median
$204.17
Typical High
$223.87
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$32.36
Median
$40.74
Typical High
$44.67
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$21.38
Median
$26.92
Typical High
$30.20

Where Kentucky sits

The same service costs 3.5 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 48th of 51

$251

AK $832FL $234

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.