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Light-Activated Drug Treatment for Retina Vessels

Massachusetts rates for HCPCS 67221

This is a treatment for abnormal blood vessel growth beneath the retina, often related to macular degeneration, where a light-sensitive medication is given through an intravenous line and then activated with a special low-energy light aimed into the eye. Activating the medication seals off the abnormal vessels while sparing the surrounding healthy retinal tissue.

Rates data updated July 2026.

How much does Light-Activated Drug Treatment for Retina Vessels cost?

$347

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $347 from a physician practice, and about $1,288 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$347$251 to $501
FacilityA hospital or hospital-owned outpatient department$1,288$288 to $2,512

How much rates vary

Facilitymedian $1,288 · 10th to 90th $240 to $3,715Professionalmedian $347 · 10th to 90th $204 to $741
$100.0$1.0K$10.0Kfacility $1,288professional $347

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$2,238.72
Typical High
$3,715.35
Aetna
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$288.40
Typical High
$562.34
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$1,148.15
Typical High
$3,801.89
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$363.08
Typical High
$831.76
BCBS
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$239.88
Typical High
$549.54
BCBS
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$489.78
Typical High
$724.44
Cigna
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
Cigna
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$436.52
Typical High
$758.58
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$245.47
Typical High
$3,630.78
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$380.19
Typical High
$489.78
Harvard Pilgrim
Setting
Facility
Modifier
Global
Typical Low
$1,148.15
Median
$2,511.89
Typical High
$7,079.46
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$346.74
Typical High
$741.31
Health New England
Setting
Professional
Modifier
Global
Typical Low
$602.56
Median
$602.56
Typical High
$602.56
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$1,148.15
Typical High
$3,801.89
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$363.08
Typical High
$831.76
United
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$1,949.84
Typical High
$5,623.41
United
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$389.05
Typical High
$776.25

Where Massachusetts sits

The same service costs 3.8 times more in Wyoming than in West Virginia. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Massachusetts $347 · 21st of 51
WY $977WV $257

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.