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25-Gene Medication Response Test

Indiana rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated July 2026.

How much does 25-Gene Medication Response Test cost?

$741

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $603 from a physician practice, and about $891 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$603$589 to $692
FacilityA hospital or hospital-owned outpatient department$891$741 to $1,622

How much rates vary

Facilitymedian $891 · 10th to 90th $741 to $2,239Professionalmedian $603 · 10th to 90th $447 to $851
$200.0$500.0$1.0K$2.0K$5.0K$10.0Kfacility $891professional $603

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$741.31
Median
$1,148.15
Typical High
$2,238.72
Aetna
Setting
Professional
Modifier
Global
Typical Low
$501.19
Median
$602.56
Typical High
$630.96
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$741.31
Median
$741.31
Typical High
$2,238.72
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$691.83
Median
$691.83
Typical High
$1,479.11
CareSource
Setting
Facility
Modifier
Global
Typical Low
$724.44
Median
$10,715.19
Typical High
$16,218.10
Cigna
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$1,230.27
Typical High
$2,884.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$851.14
Median
$912.01
Typical High
$2,238.72
United
Setting
Facility
Modifier
Global
Typical Low
$741.31
Median
$741.31
Typical High
$891.25
United
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$812.83

Where Indiana sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Indiana $741 · 14th of 51
AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.