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25-Gene Medication Response Test

Connecticut rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated October 2026.

How much does 25-Gene Medication Response Test cost?

$490

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $490 for this service. Most negotiated rates run $407 to $832.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $1,175 · 10th to 90th $794 to $1,950Professionalmedian $447 · 10th to 90th $380 to $832
$500$1K$2Kfacility $1,175professional $447

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$489.78
Typical High
$524.81
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$794.33
Median
$1,174.90
Typical High
$1,819.70
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$380.19
Median
$446.68
Typical High
$831.76
Cigna
Setting
Facility
Modifier
None
Typical Low
$478.63
Median
$1,778.28
Typical High
$4,265.80
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$776.25
Median
$1,348.96
Typical High
$1,380.38
United
Setting
Professional
Modifier
None
Typical Low
$309.03
Median
$446.68
Typical High
$954.99
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$204.17
Median
$245.47
Typical High
$257.04
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$81.28
Median
$97.72
Typical High
$104.71

Where Connecticut sits

The same service costs 58.9 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 44th of 51

$490

TX $3,715AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.