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25-Gene Medication Response Test

South Dakota rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated July 2026.

Facilitymedian $851 · 10th–90th $525$1,1750%20%40%10th90th$851Professionalmedian $1,413 · 10th–90th $501$1,9500%10%20%10th90th$1,413$500.0$1.0K$2.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Small sample; interpret with caution. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$524.81
Median
$851.14
Typical High
$851.14
Aetna
Setting
Professional
Modifier
Global
Typical Low
$501.19
Median
$575.44
Typical High
$691.83
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,412.54
Typical High
$1,778.28
Medica
Setting
Facility
Modifier
Global
Typical Low
$707.95
Median
$707.95
Typical High
$1,348.96
Medica
Setting
Professional
Modifier
Global
Typical Low
$380.19
Median
$380.19
Typical High
$3,715.35
Midlands
Setting
Professional
Modifier
Global
Typical Low
$891.25
Median
$891.25
Typical High
$891.25
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,737.80
Typical High
$2,041.74
United
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$977.24
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$741.31
Median
$741.31
Typical High
$741.31