go back

25-Gene Medication Response Test

South Dakota rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated October 2026.

How much does 25-Gene Medication Response Test cost?

$741

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $741 for this service. Most negotiated rates run $661 to $1,413.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $832 · 10th to 90th $708 to $851Professionalmedian $741 · 10th to 90th $380 to $1,778
$500$1K$2Kfacility $832professional $741

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$524.81
Median
$524.81
Typical High
$851.14
Aetna
Setting
Professional
Modifier
None
Typical Low
$501.19
Median
$501.19
Typical High
$691.83
Cigna
Setting
Professional
Modifier
None
Typical Low
$851.14
Median
$1,412.54
Typical High
$1,778.28
Medica
Setting
Facility
Modifier
None
Typical Low
$707.95
Median
$831.76
Typical High
$831.76
Medica
Setting
Professional
Modifier
None
Typical Low
$380.19
Median
$660.69
Typical High
$1,445.44
Midlands
Setting
Professional
Modifier
None
Typical Low
$912.01
Median
$912.01
Typical High
$912.01
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,041.74
United
Setting
Professional
Modifier
None
Typical Low
$309.03
Median
$446.68
Typical High
$741.31
Wellmark
Setting
Professional
Modifier
None
Typical Low
$741.31
Median
$741.31
Typical High
$741.31

Where South Dakota sits

The same service costs 58.9 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 15th of 51

$741

TX $3,715AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.