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25-Gene Medication Response Test

Nebraska rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated October 2026.

How much does 25-Gene Medication Response Test cost?

$490

Typical negotiated rate. In Nebraska, October 2026.

Insurers have agreed to pay about $490 for this service. The price depends on where it is billed: about $447 from a physician practice, and about $1,202 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$447$447 to $1,413
FacilityA hospital or hospital-owned outpatient department$1,202$977 to $1,778

How much rates vary

Facilitymedian $1,202 · 10th to 90th $891 to $2,512Professionalmedian $447 · 10th to 90th $427 to $3,715
$500$1K$2Kfacility $1,202professional $447

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$524.81
Median
$1,778.28
Typical High
$3,715.35
Aetna
Setting
Professional
Modifier
None
Typical Low
$489.78
Median
$489.78
Typical High
$1,778.28
BCBS Nebraska
Setting
Facility
Modifier
None
Typical Low
$891.25
Median
$1,202.26
Typical High
$2,454.71
Cigna
Setting
Professional
Modifier
None
Typical Low
$912.01
Median
$1,412.54
Typical High
$1,778.28
Medica
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$1,122.02
Typical High
$3,548.13
Medica
Setting
Professional
Modifier
None
Typical Low
$446.68
Median
$446.68
Typical High
$3,715.35
Midlands
Setting
Professional
Modifier
None
Typical Low
$912.01
Median
$1,348.96
Typical High
$1,348.96
Midlands
Setting
Professional
Modifier
None
Typical Low
$1,348.96
Median
$1,348.96
Typical High
$1,348.96
United
Setting
Professional
Modifier
None
Typical Low
$426.58
Median
$446.68
Typical High
$2,187.76

Where Nebraska sits

The same service costs 58.9 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 45th of 51

$490

TX $3,715AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.