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25-Gene Medication Response Test

Minnesota rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated July 2026.

How much does 25-Gene Medication Response Test cost?

$741

Typical negotiated rate. In Minnesota, July 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $741 from a physician practice, and about $1,995 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$741$692 to $851
FacilityA hospital or hospital-owned outpatient department$1,995$741 to $2,884

How much rates vary

Facilitymedian $1,995 · 10th to 90th $741 to $5,495Professionalmedian $741 · 10th to 90th $589 to $1,072
$500.0$1.0K$2.0K$5.0Kfacility $1,995professional $741

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$691.83
Median
$691.83
Typical High
$691.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$562.34
Typical High
$891.25
BCBS
Setting
Facility
Modifier
Global
Typical Low
$724.44
Median
$741.31
Typical High
$741.31
BCBS
Setting
Professional
Modifier
Global
Typical Low
$588.84
Median
$741.31
Typical High
$741.31
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,621.81
Median
$2,511.89
Typical High
$6,918.31
Cigna
Setting
Professional
Modifier
Global
Typical Low
$870.96
Median
$1,071.52
Typical High
$1,513.56
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$1,949.84
Median
$2,398.83
Typical High
$5,495.41
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$851.14
Median
$851.14
Typical High
$1,412.54
Medica
Setting
Facility
Modifier
Global
Typical Low
$562.34
Median
$1,288.25
Typical High
$2,238.72
Medica
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$1,949.84
United
Setting
Facility
Modifier
Global
Typical Low
$851.14
Median
$851.14
Typical High
$851.14
United
Setting
Professional
Modifier
Global
Typical Low
$380.19
Median
$741.31
Typical High
$1,621.81

Where Minnesota sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Minnesota $741 · 24th of 51
AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.