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25-Gene Medication Response Test

Illinois rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated July 2026.

How much does 25-Gene Medication Response Test cost?

$891

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $891 for this service. The price depends on where it is billed: about $603 from a physician practice, and about $1,175 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$603$447 to $891
FacilityA hospital or hospital-owned outpatient department$1,175$891 to $1,514

How much rates vary

Facilitymedian $1,175 · 10th to 90th $741 to $1,698Professionalmedian $603 · 10th to 90th $407 to $1,514
$100.0$200.0$500.0$1.0K$2.0K$5.0Kfacility $1,175professional $603

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$724.44
Median
$1,174.90
Typical High
$1,584.89
Aetna
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$602.56
Typical High
$1,513.56
BCBS
Setting
Facility
Modifier
Global
Typical Low
$891.25
Median
$1,000.00
Typical High
$1,202.26
Cigna
Setting
Facility
Modifier
Global
Typical Low
$870.96
Median
$1,621.81
Typical High
$3,715.35
Cigna
Setting
Professional
Modifier
Global
Typical Low
$870.96
Median
$912.01
Typical High
$1,071.52
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$1,000.00
Typical High
$1,380.38
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$954.99
Median
$954.99
Typical High
$954.99
United
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$891.25
Typical High
$1,479.11
United
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$741.31

Where Illinois sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Illinois $891 · 8th of 51
AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.