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25-Gene Medication Response Test

Illinois rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated October 2026.

How much does 25-Gene Medication Response Test cost?

$741

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $468 from a physician practice, and about $1,202 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$468$407 to $813
FacilityA hospital or hospital-owned outpatient department$1,202$1,000 to $2,042

How much rates vary

Facilitymedian $1,202 · 10th to 90th $832 to $3,090Professionalmedian $468 · 10th to 90th $309 to $1,148
$200$500$1K$2K$5Kfacility $1,202professional $468

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$724.44
Median
$1,698.24
Typical High
$2,238.72
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$457.09
Median
$575.44
Typical High
$724.44
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$602.56
Median
$602.56
Typical High
$645.65
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$302.00
Median
$302.00
Typical High
$316.23
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$123.03
Median
$123.03
Typical High
$128.82
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$891.25
Median
$1,000.00
Typical High
$1,202.26
Cigna
Setting
Facility
Modifier
None
Typical Low
$831.76
Median
$1,778.28
Typical High
$3,388.44
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$870.96
Median
$912.01
Typical High
$1,071.52
Hally Health
Setting
Professional
Modifier
None
Typical Low
$660.69
Median
$1,047.13
Typical High
$1,479.11
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$954.99
Median
$954.99
Typical High
$954.99
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$309.03
Median
$446.68
Typical High
$741.31

Where Illinois sits

The same service costs 58.9 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 17th of 51

$741

TX $3,715AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.