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25-Gene Medication Response Test

Virginia rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated October 2026.

How much does 25-Gene Medication Response Test cost?

$692

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $692 for this service. The price depends on where it is billed: about $692 from a physician practice, and about $1,230 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$692$537 to $741
FacilityA hospital or hospital-owned outpatient department$1,230$759 to $1,905

How much rates vary

Facilitymedian $1,230 · 10th to 90th $631 to $3,631Professionalmedian $692 · 10th to 90th $407 to $1,072
$500$1K$2K$5Kfacility $1,230professional $692

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$630.96
Typical High
$1,737.80
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$562.34
Median
$562.34
Typical High
$630.96
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$2,818.38
Median
$3,630.78
Typical High
$4,570.88
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$512.86
Median
$691.83
Typical High
$933.25
CareFirst
Setting
Professional
Modifier
None (both parts)
Typical Low
$537.03
Median
$588.84
Typical High
$707.95
Cigna
Setting
Facility
Modifier
None
Typical Low
$758.58
Median
$1,230.27
Typical High
$1,819.70
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$707.95
Median
$812.83
Typical High
$1,047.13
Medcost
Setting
Facility
Modifier
None
Typical Low
$954.99
Median
$954.99
Typical High
$954.99
Medcost
Setting
Professional
Modifier
None (both parts)
Typical Low
$478.63
Median
$478.63
Typical High
$741.31
Sentara
Setting
Facility
Modifier
None
Typical Low
$524.81
Median
$891.25
Typical High
$1,778.28
Sentara
Setting
Professional
Modifier
None (both parts)
Typical Low
$676.08
Median
$851.14
Typical High
$1,445.44
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$309.03
Median
$446.68
Typical High
$1,023.29
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$562.34
Median
$562.34
Typical High
$562.34
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$275.42
Median
$275.42
Typical High
$316.23
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$112.20
Median
$112.20
Typical High
$125.89
Sentara
Setting
Professional
Modifier
TC · Technical part
Typical Low
$741.31
Median
$851.14
Typical High
$1,380.38

Where Virginia sits

The same service costs 58.9 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 31st of 51

$692

TX $3,715AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.