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25-Gene Medication Response Test

Missouri rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated October 2026.

How much does 25-Gene Medication Response Test cost?

$724

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $724 for this service. The price depends on where it is billed: about $724 from a physician practice, and about $1,622 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$724$537 to $1,122
FacilityA hospital or hospital-owned outpatient department$1,622$1,023 to $1,905

How much rates vary

Facilitymedian $1,622 · 10th to 90th $741 to $3,548Professionalmedian $724 · 10th to 90th $447 to $3,715
$500$1K$2K$5Kfacility $1,622professional $724

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$724.44
Median
$1,023.29
Typical High
$2,570.40
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$645.65
Median
$724.44
Typical High
$724.44
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$691.83
Median
$794.33
Typical High
$1,348.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,023.29
Median
$1,659.59
Typical High
$6,025.60
Medica
Setting
Facility
Modifier
None
Typical Low
$645.65
Median
$1,288.25
Typical High
$3,548.13
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$371.54
Median
$741.31
Typical High
$3,715.35
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$3,801.89
Median
$3,801.89
Typical High
$3,801.89
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$309.03
Median
$446.68
Typical High
$1,000.00
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$630.96
Median
$645.65
Typical High
$724.44
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$316.23
Median
$316.23
Typical High
$389.05
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$125.89
Median
$128.82
Typical High
$158.49

Where Missouri sits

The same service costs 58.9 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 26th of 51

$724

TX $3,715AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.