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25-Gene Medication Response Test

Massachusetts rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated July 2026.

Facilitymedian $1,698 · 10th–90th $525$2,5700%10%10th90th$1,698Professionalmedian $741 · 10th–90th $447$1,4130%50%10th90th$741$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$524.81
Median
$1,659.59
Typical High
$2,398.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$524.81
Typical High
$602.56
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$812.83
Median
$1,995.26
Typical High
$3,548.13
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$741.31
Typical High
$2,454.71
Cigna
Setting
Facility
Modifier
Global
Typical Low
$501.19
Median
$575.44
Typical High
$1,202.26
Cigna
Setting
Professional
Modifier
Global
Typical Low
$912.01
Median
$912.01
Typical High
$1,122.02
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,071.52
Typical High
$1,258.93
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$741.31
Median
$741.31
Typical High
$1,230.27
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$812.83
Median
$1,995.26
Typical High
$3,548.13
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$741.31
Typical High
$2,454.71
United
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$660.69
Typical High
$891.25
United
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$741.31
Typical High
$1,698.24