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25-Gene Medication Response Test

North Carolina rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated July 2026.

How much does 25-Gene Medication Response Test cost?

$589

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $589 for this service. The price depends on where it is billed: about $589 from a physician practice, and about $646 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$589$589 to $741
FacilityA hospital or hospital-owned outpatient department$646$589 to $912

How much rates vary

Facilitymedian $646 · 10th to 90th $589 to $1,950Professionalmedian $589 · 10th to 90th $490 to $1,175
$500.0$1.0K$2.0K$5.0Kfacility $646professional $589

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$588.84
Typical High
$1,621.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$588.84
Typical High
$588.84
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,659.59
Median
$1,659.59
Typical High
$2,344.23
BCBS
Setting
Professional
Modifier
Global
Typical Low
$630.96
Median
$741.31
Typical High
$1,348.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$1,949.84
Typical High
$3,388.44
Medcost
Setting
Facility
Modifier
Global
Typical Low
$562.34
Median
$660.69
Typical High
$977.24
Medcost
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$478.63
United
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$870.96
Typical High
$912.01
United
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$446.68
Typical High
$794.33
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$3,548.13
Median
$3,548.13
Typical High
$3,548.13
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$3,715.35
Median
$3,715.35
Typical High
$5,623.41

Where North Carolina sits

The same service costs 3.7 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Carolina $589 · 38th of 51
AK $1,660WY $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.