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25-Gene Medication Response Test

Michigan rates for HCPCS 0348U

Helps a clinician pick medications that suit your genetics and avoid ones your body may process poorly. Twenty-five genes that affect how the body handles medicines are examined in either whole blood or a cheek (buccal) swab, and each gene is reported as a metabolizer type. This version reports the gene results themselves, without an accompanying analysis of individual drug interactions.

Rates data updated October 2026.

How much does 25-Gene Medication Response Test cost?

$676

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $676 for this service. The price depends on where it is billed: about $525 from a physician practice, and about $708 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$525$490 to $741
FacilityA hospital or hospital-owned outpatient department$708$708 to $1,096

How much rates vary

Facilitymedian $708 · 10th to 90th $676 to $1,862Professionalmedian $525 · 10th to 90th $447 to $912
$500$1K$2Kfacility $708professional $525

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$707.95
Median
$707.95
Typical High
$1,096.48
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$354.81
Median
$354.81
Typical High
$549.54
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$141.25
Median
$141.25
Typical High
$218.78
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$588.84
Median
$707.95
Typical High
$1,513.56
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$707.95
Median
$724.44
Typical High
$741.31
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$338.84
Median
$363.08
Typical High
$371.54
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$134.90
Median
$144.54
Typical High
$151.36
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$524.81
Median
$524.81
Typical High
$524.81
BCBS Michigan
Setting
Professional
Modifier
None (both parts)
Typical Low
$489.78
Median
$524.81
Typical High
$524.81
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$870.96
Median
$912.01
Typical High
$1,122.02
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$707.95
Median
$707.95
Typical High
$2,089.30
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$354.81
Median
$354.81
Typical High
$549.54
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$141.25
Median
$141.25
Typical High
$218.78
Health Alliance Plan
Setting
Professional
Modifier
None (both parts)
Typical Low
$707.95
Median
$794.33
Typical High
$1,000.00
Health Alliance Plan
Setting
Professional
Modifier
26 · Professional part
Typical Low
$707.95
Median
$707.95
Typical High
$707.95
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$141.25
Median
$141.25
Typical High
$141.25
Priority Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$870.96
Median
$870.96
Typical High
$912.01
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$309.03
Median
$446.68
Typical High
$741.31

Where Michigan sits

The same service costs 58.9 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 32nd of 51

$676

TX $3,715AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.