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Tumor Profile Of 505 Genes With Instability Measures

Nationwide rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated June 2026.

Facilitymedian $4,677 · 10th–90th $2,399$13,8040%10%10th90th$4,677Professionalmedian $2,399 · 10th–90th $1,585$3,5480%20%10th90th$2,399$5.0$20.0$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$5,011.87
Typical High
$13,182.57
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$2,344.23
Typical High
$3,388.44
BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,454.71
Median
$4,897.79
Typical High
$14,791.08
BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,288.25
Typical High
$3,981.07
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,995.26
Median
$5,623.41
Typical High
$12,882.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,388.44
Median
$4,265.80
Typical High
$7,943.28
United
Setting
Facility
Modifier
Global
Typical Low
$1,380.38
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,467.37