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Tumor Profile Of 505 Genes With Instability Measures

Iowa rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,818

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $2,818 for this service. The price depends on where it is billed: about $2,512 from a physician practice, and about $4,467 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,512$2,239 to $3,162
FacilityA hospital or hospital-owned outpatient department$4,467$2,951 to $7,413

How much rates vary

Facilitymedian $4,467 · 10th to 90th $2,239 to $8,511Professionalmedian $2,512 · 10th to 90th $1,738 to $6,310
$2K$5K$10Kfacility $4,467professional $2,512

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$6,918.31
Typical High
$8,511.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$2,238.72
Typical High
$2,818.38
Cigna
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$3,467.37
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$5,623.41
Typical High
$6,918.31
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$3,801.89
Typical High
$5,248.07
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$3,467.37
Typical High
$7,413.10
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$11,748.98
Midlands
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$3,630.78
Typical High
$11,481.54
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,162.28
Typical High
$6,165.95
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$6,456.54
United
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$1,737.80
Typical High
$7,413.10
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$2,951.21

Where Iowa sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 20th of 51

$2,818

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.