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Tumor Profile Of 505 Genes With Instability Measures

Missouri rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,818

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $2,818 for this service. The price depends on where it is billed: about $2,512 from a physician practice, and about $4,169 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,512$1,230 to $3,388
FacilityA hospital or hospital-owned outpatient department$4,169$2,951 to $5,129

How much rates vary

Facilitymedian $4,169 · 10th to 90th $2,630 to $6,761Professionalmedian $2,512 · 10th to 90th $1,175 to $5,012
$2K$5K$10Kfacility $4,169professional $2,512

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,818.38
Median
$4,897.79
Typical High
$6,760.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,454.71
Median
$2,511.89
Typical High
$5,888.44
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,348.96
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$4,168.69
Median
$6,165.95
Typical High
$15,135.61
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,511.89
Median
$3,467.37
Typical High
$13,803.84
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$14,454.40
United
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,388.44

Where Missouri sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 21st of 51

$2,818

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.