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Tumor Profile Of 505 Genes With Instability Measures

Maryland rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,188

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $2,188 for this service. Most negotiated rates run $1,905 to $2,399.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $1,230 · 10th to 90th $1,230 to $2,239Professionalmedian $2,188 · 10th to 90th $1,318 to $2,570
$2Kfacility $1,230professional $2,188

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$2,187.76
Typical High
$2,454.71
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$2,630.27
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$1,548.82
Typical High
$1,548.82
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,388.44
Typical High
$4,365.16
United
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$2,238.72
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,318.26
Typical High
$2,570.40
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$1,445.44
Median
$1,445.44
Typical High
$1,445.44

Where Maryland sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 44th of 51

$2,188

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.