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Tumor Profile Of 505 Genes With Instability Measures

Florida rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,089

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $2,089 for this service. The price depends on where it is billed: about $2,042 from a physician practice, and about $5,370 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,042$1,738 to $2,399
FacilityA hospital or hospital-owned outpatient department$5,370$2,630 to $8,511

How much rates vary

Facilitymedian $5,370 · 10th to 90th $2,089 to $15,849Professionalmedian $2,042 · 10th to 90th $1,660 to $2,951
$200$500$1K$2K$5K$10Kfacility $5,370professional $2,042

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,089.30
Median
$7,079.46
Typical High
$15,848.93
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,041.74
Typical High
$2,630.27
AvMed
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$2,951.21
AvMed
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$2,951.21
Typical High
$2,951.21
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,513.56
Median
$2,238.72
Typical High
$11,748.98
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,548.13
Median
$4,265.80
Typical High
$14,125.38
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$5,370.32
Median
$5,370.32
Typical High
$5,370.32
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$1,737.80
Typical High
$2,454.71
Molina
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,344.23
Typical High
$2,951.21
United
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$2,630.27
Typical High
$2,951.21
United
Setting
Professional
Modifier
Global
Typical Low
$1,023.29
Median
$1,230.27
Typical High
$3,890.45
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$1,737.80
Typical High
$2,951.21

Where Florida sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 47th of 51

$2,089

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.