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Tumor Profile Of 505 Genes With Instability Measures

North Carolina rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,455

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $2,455 for this service. The price depends on where it is billed: about $2,344 from a physician practice, and about $2,951 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,344$2,344 to $2,951
FacilityA hospital or hospital-owned outpatient department$2,951$2,512 to $3,467

How much rates vary

Facilitymedian $2,951 · 10th to 90th $2,344 to $5,129Professionalmedian $2,344 · 10th to 90th $1,950 to $4,677
$2K$5K$10Kfacility $2,951professional $2,344

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,344.23
Median
$2,951.21
Typical High
$3,467.37
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,344.23
Typical High
$2,344.23
BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,897.79
Median
$6,456.54
Typical High
$9,332.54
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,454.71
Median
$2,951.21
Typical High
$5,248.07
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$7,585.78
Typical High
$13,182.57
Medcost
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$2,630.27
Typical High
$4,073.80
Medcost
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$1,905.46
Typical High
$1,905.46
United
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$3,467.37
Typical High
$3,548.13
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,090.30
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$13,803.84
Median
$13,803.84
Typical High
$13,803.84
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$14,454.40
Median
$14,454.40
Typical High
$21,877.62

Where North Carolina sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 31st of 51

$2,455

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.