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Tumor Profile Of 505 Genes With Instability Measures

Indiana rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,399

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $2,399 for this service. The price depends on where it is billed: about $2,399 from a physician practice, and about $3,236 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,399$1,585 to $2,399
FacilityA hospital or hospital-owned outpatient department$3,236$2,951 to $6,457

How much rates vary

Facilitymedian $3,236 · 10th to 90th $2,951 to $8,710Professionalmedian $2,399 · 10th to 90th $1,175 to $2,512
$2K$5K$10K$20Kfacility $3,236professional $2,399

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$4,570.88
Typical High
$8,709.64
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$2,398.83
Typical High
$2,511.89
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$8,709.64
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$2,238.72
CareSource
Setting
Facility
Modifier
Global
Typical Low
$2,570.40
Median
$4,570.88
Typical High
$63,095.73
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,905.46
Median
$4,786.30
Typical High
$11,481.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$3,548.13
Typical High
$8,709.64
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,235.94

Where Indiana sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 33rd of 51

$2,399

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.