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Tumor Profile Of 505 Genes With Instability Measures

Connecticut rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,291

Typical negotiated rate. In Connecticut, July 2026.

Insurers have agreed to pay about $2,291 for this service. The price depends on where it is billed: about $1,905 from a physician practice, and about $4,169 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$1,905$1,585 to $2,291
FacilityA hospital or hospital-owned outpatient department$4,169$2,951 to $5,888

How much rates vary

Facilitymedian $4,169 · 10th to 90th $2,951 to $7,586Professionalmedian $1,905 · 10th to 90th $1,549 to $3,162
$2K$5K$10Kfacility $4,169professional $1,905

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$3,981.07
Typical High
$6,606.93
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$1,905.46
Typical High
$2,187.76
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,890.45
Median
$4,786.30
Typical High
$7,943.28
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$2,884.03
Typical High
$3,890.45
Cigna
Setting
Facility
Modifier
Global
Typical Low
$4,677.35
Median
$8,709.64
Typical High
$16,595.87
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$5,370.32
Median
$5,370.32
Typical High
$5,370.32
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$2,951.21
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,801.89

Where Connecticut sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 41st of 51

$2,291

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.