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Tumor Profile Of 505 Genes With Instability Measures

Illinois rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,754

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $2,754 for this service. The price depends on where it is billed: about $2,399 from a physician practice, and about $3,802 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,399$2,138 to $2,754
FacilityA hospital or hospital-owned outpatient department$3,802$2,951 to $5,888

How much rates vary

Facilitymedian $3,802 · 10th to 90th $2,399 to $6,026Professionalmedian $2,399 · 10th to 90th $1,585 to $5,012
$200$500$1K$2K$5K$10Kfacility $3,802professional $2,399

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$3,801.89
Typical High
$6,025.60
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,819.70
Median
$2,398.83
Typical High
$6,025.60
BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$3,981.07
Typical High
$4,786.30
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$4,466.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$3,388.44
Median
$6,309.57
Typical High
$13,489.63
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,388.44
Median
$3,548.13
Typical High
$4,265.80
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$3,981.07
Typical High
$5,370.32
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$3,801.89
Typical High
$3,801.89
Molina
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$5,888.44
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,951.21

Where Illinois sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 23rd of 51

$2,754

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.