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Tumor Profile Of 505 Genes With Instability Measures

Massachusetts rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated June 2026.

Facilitymedian $6,607 · 10th–90th $2,042$9,1200%10%20%10th90th$6,607Professionalmedian $2,951 · 10th–90th $1,905$4,8980%20%40%10th90th$2,951$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,041.74
Median
$6,606.93
Typical High
$9,120.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,344.23
Typical High
$2,818.38
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$3,235.94
Median
$7,762.47
Typical High
$13,803.84
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$9,772.37
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,995.26
Median
$2,290.87
Typical High
$4,677.35
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,548.13
Median
$3,548.13
Typical High
$4,265.80
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$5,011.87
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$4,168.69
Typical High
$5,011.87
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$4,897.79
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$3,235.94
Median
$7,762.47
Typical High
$13,803.84
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$9,772.37
United
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$6,606.93