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Tumor Profile Of 505 Genes With Instability Measures

Nebraska rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$1,905

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $1,905 for this service. The price depends on where it is billed: about $1,905 from a physician practice, and about $2,754 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$1,905$1,905 to $4,266
FacilityA hospital or hospital-owned outpatient department$2,754$1,738 to $6,918

How much rates vary

Facilitymedian $2,754 · 10th to 90th $1,230 to $7,762Professionalmedian $1,905 · 10th to 90th $1,738 to $6,457
$1K$2K$5K$10Kfacility $2,754professional $1,905

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,041.74
Median
$7,762.47
Typical High
$14,454.40
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$1,905.46
Typical High
$1,905.46
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,174.90
Median
$1,513.56
Typical High
$2,951.21
BCBS
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$4,570.88
Typical High
$4,786.30
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,981.07
Median
$6,309.57
Typical High
$7,943.28
Medica
Setting
Facility
Modifier
Global
Typical Low
$1,047.13
Median
$1,905.46
Typical High
$13,803.84
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$8,511.38
Midlands
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$3,467.37
United
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$2,754.23
Typical High
$2,951.21
United
Setting
Professional
Modifier
Global
Typical Low
$1,659.59
Median
$1,737.80
Typical High
$8,128.31

Where Nebraska sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 50th of 51

$1,905

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.