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Tumor Profile Of 505 Genes With Instability Measures

South Dakota rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$3,388

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $3,388 for this service. Most negotiated rates run $2,291 to $6,761.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $3,311 · 10th to 90th $2,042 to $4,677Professionalmedian $3,467 · 10th to 90th $1,950 to $7,079
$2K$5Kfacility $3,311professional $3,467

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,041.74
Median
$3,311.31
Typical High
$3,311.31
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,290.87
Typical High
$2,754.23
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$5,623.41
Typical High
$6,918.31
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$2,818.38
Typical High
$5,370.32
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,479.11
Median
$1,479.11
Typical High
$14,454.40
Midlands
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$3,467.37
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$6,760.83
Typical High
$7,943.28
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,951.21
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$2,951.21

Where South Dakota sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 8th of 51

$3,388

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.