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Tumor Profile Of 505 Genes With Instability Measures

Virginia rates for HCPCS 0250U

Profiles a solid tumor by sequencing 505 genes to find the changes driving it. It also reports two whole-tumor measures — microsatellite instability and tumor mutation burden — which describe how unstable and how heavily mutated the tumor's DNA is.

Rates data updated July 2026.

How much does Tumor Profile Of 505 Genes With Instability Measures cost?

$2,399

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $2,399 for this service. The price depends on where it is billed: about $2,188 from a physician practice, and about $3,981 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,188$1,230 to $2,455
FacilityA hospital or hospital-owned outpatient department$3,981$2,951 to $6,457

How much rates vary

Facilitymedian $3,981 · 10th to 90th $2,188 to $12,303Professionalmedian $2,188 · 10th to 90th $1,175 to $3,802
$2K$5K$10Kfacility $3,981professional $2,188

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$5,495.41
Typical High
$7,244.36
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$2,398.83
Typical High
$5,495.41
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$11,748.98
Median
$15,135.61
Typical High
$18,197.01
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$1,949.84
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$2,238.72
Median
$2,511.89
Typical High
$2,951.21
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$7,244.36
Typical High
$14,791.08
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,235.94
Typical High
$4,073.80
Medcost
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$2,951.21
Typical High
$5,011.87
Medcost
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$1,905.46
Typical High
$6,165.95
Sentara
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$3,388.44
Typical High
$6,760.83
Sentara
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$3,388.44
Typical High
$6,760.83
United
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,445.44
Typical High
$3,388.44

Where Virginia sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 35th of 51

$2,399

AK $6,607WY $1,738

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.