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Analysis Of One Gene

Nationwide rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated July 2026.

How much does Analysis Of One Gene cost?

$195

Typical negotiated rate. Nationwide, July 2026.

Insurers have agreed to pay about $195 for this service. The price depends on where it is billed: about $166 from a physician practice, and about $288 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 67 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$166$129 to $209
FacilityA hospital or hospital-owned outpatient department$288$195 to $490

How much rates vary

Facilitymedian $288 · 10th to 90th $155 to $891Professionalmedian $166 · 10th to 90th $93 to $372
$1.0$10.0$100.0$1.0K$10.0K$100.0Kfacility $288professional $166

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$302.00
Typical High
$831.76
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$158.49
Typical High
$354.81
BCBS
Setting
Facility
Modifier
Global
Typical Low
$194.98
Median
$302.00
Typical High
$891.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$97.72
Typical High
$316.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$389.05
Typical High
$870.96
Cigna
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$223.87
Typical High
$457.09
United
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$194.98
Typical High
$234.42
United
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$114.82
Typical High
$281.84

What it costs in each state

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

AK $437DE $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.