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Analysis Of One Gene

Minnesota rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated October 2026.

How much does Analysis Of One Gene cost?

$195

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $195 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $195 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$166 to $234
FacilityA hospital or hospital-owned outpatient department$195$182 to $457

How much rates vary

Facilitymedian $195 · 10th to 90th $182 to $759Professionalmedian $195 · 10th to 90th $115 to $389
$100$200$500$1Kfacility $195professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$181.97
Aetna
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$234.42
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$194.98
Typical High
$346.74
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$154.88
Median
$173.78
Typical High
$194.98
Cigna
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$616.60
Typical High
$1,819.70
Cigna
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$251.19
Typical High
$371.54
Health Partners
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$588.84
Typical High
$1,412.54
Health Partners
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$223.87
Typical High
$346.74
Medica
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$309.03
Typical High
$389.05
Medica
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$213.80
Typical High
$954.99
United
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$234.42
United
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$154.88
Typical High
$457.09
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$91.20
Typical High
$91.20
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$36.31
Typical High
$36.31
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$91.20
Typical High
$114.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$36.31
Typical High
$46.77

Where Minnesota sits

The same service costs 8.3 times more in Texas than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 26th of 51

$195

TX $955DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.