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Analysis Of One Gene

Maryland rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated October 2026.

How much does Analysis Of One Gene cost?

$145

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $145 for this service. Most negotiated rates run $120 to $155.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $145 · 10th to 90th $87 to $195
$100$200$500professional $145

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$144.54
Typical High
$151.36
CareFirst
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$154.88
Typical High
$154.88
Cigna
Setting
Professional
Modifier
None
Typical Low
$102.33
Median
$141.25
Typical High
$562.34
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$234.42
Typical High
$288.40
United
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$97.72
Typical High
$169.82
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$97.72
Typical High
$154.88
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$70.79
Median
$72.44
Typical High
$75.86
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.84
Median
$28.84
Typical High
$30.90

Where Maryland sits

The same service costs 8.3 times more in Texas than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 44th of 51

$145

TX $955DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.