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Analysis Of One Gene

South Dakota rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated July 2026.

How much does Analysis Of One Gene cost?

$309

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $309 for this service. The price depends on where it is billed: about $234 from a physician practice, and about $372 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$234$151 to $447
FacilityA hospital or hospital-owned outpatient department$372$372 to $372

How much rates vary

Facilitymedian $372 · 10th to 90th $219 to $372Professionalmedian $234 · 10th to 90th $129 to $468
$100.0$200.0$500.0$1.0Kfacility $372professional $234

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$218.78
Typical High
$218.78
Aetna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$151.36
Typical High
$181.97
Cigna
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$371.54
Typical High
$371.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$371.54
Typical High
$457.09
Medica
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$218.78
Typical High
$354.81
Medica
Setting
Professional
Modifier
Global
Typical Low
$97.72
Median
$97.72
Typical High
$954.99
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$446.68
Typical High
$537.03
United
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$114.82
Typical High
$257.04
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$194.98
Typical High
$194.98

Where South Dakota sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $309 · 2nd of 51
AK $437DE $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.