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Analysis Of One Gene

Colorado rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated October 2026.

How much does Analysis Of One Gene cost?

$257

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $257 for this service. The price depends on where it is billed: about $115 from a physician practice, and about $562 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$115$81.28 to $251
FacilityA hospital or hospital-owned outpatient department$562$363 to $676

How much rates vary

Facilitymedian $562 · 10th to 90th $148 to $891Professionalmedian $115 · 10th to 90th $81 to $398
$100$200$500$1Kfacility $562professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$407.38
Typical High
$891.25
Aetna
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$147.91
Typical High
$204.17
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$204.17
Median
$575.44
Typical High
$891.25
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$81.28
Typical High
$426.58
Cigna
Setting
Facility
Modifier
None
Typical Low
$112.20
Median
$169.82
Typical High
$616.60
Cigna
Setting
Professional
Modifier
None
Typical Low
$89.13
Median
$102.33
Typical High
$281.84
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$147.91
Median
$173.78
Typical High
$257.04
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$275.42
Typical High
$467.74
Select Health
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$354.81
Typical High
$407.38
Select Health
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$194.98
Typical High
$288.40
United
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$234.42
Typical High
$234.42
United
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$81.28
Typical High
$144.54
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$72.44
Median
$74.13
Typical High
$102.33
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.84
Median
$29.51
Typical High
$40.74

Where Colorado sits

The same service costs 8.3 times more in Texas than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 5th of 51

$257

TX $955DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.