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Analysis Of One Gene

Illinois rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated July 2026.

How much does Analysis Of One Gene cost?

$186

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $186 for this service. The price depends on where it is billed: about $166 from a physician practice, and about $295 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$166$158 to $234
FacilityA hospital or hospital-owned outpatient department$295$200 to $389

How much rates vary

Facilitymedian $295 · 10th to 90th $158 to $501Professionalmedian $166 · 10th to 90th $115 to $389
$10.0$100.0$1.0Kfacility $295professional $166

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$295.12
Typical High
$398.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$165.96
Typical High
$331.13
BCBS
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$309.03
Typical High
$2,511.89
Cigna
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$446.68
Typical High
$891.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$89.13
Median
$234.42
Typical High
$323.59
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$346.74
Typical High
$977.24
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$251.19
Typical High
$251.19
United
Setting
Facility
Modifier
Global
Typical Low
$194.98
Median
$194.98
Typical High
$389.05
United
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$114.82
Typical High
$199.53

Where Illinois sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Illinois $186 · 26th of 51
AK $437DE $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.