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Analysis Of One Gene

Missouri rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated October 2026.

How much does Analysis Of One Gene cost?

$191

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $191 for this service. The price depends on where it is billed: about $186 from a physician practice, and about $339 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$186$93.33 to $309
FacilityA hospital or hospital-owned outpatient department$339$204 to $501

How much rates vary

Facilitymedian $339 · 10th to 90th $186 to $912Professionalmedian $186 · 10th to 90th $78 to $525
$100$200$500$1Kfacility $339professional $186

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$251.19
Typical High
$354.81
Aetna
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$165.96
Typical High
$223.87
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$891.25
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$208.93
Typical High
$363.08
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$194.98
Typical High
$363.08
Cigna
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$436.52
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
None
Typical Low
$85.11
Median
$154.88
Typical High
$257.04
Medica
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$338.84
Typical High
$912.01
Medica
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$199.53
Typical High
$954.99
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
United
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$114.82
Typical High
$257.04
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$81.28
Median
$83.18
Typical High
$112.20
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$33.11
Median
$33.11
Typical High
$44.67

Where Missouri sits

The same service costs 8.3 times more in Texas than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 27th of 51

$191

TX $955DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.