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Analysis Of One Gene

Iowa rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated October 2026.

How much does Analysis Of One Gene cost?

$204

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $204 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $347 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$115 to $355
FacilityA hospital or hospital-owned outpatient department$347$219 to $427

How much rates vary

Facilitymedian $347 · 10th to 90th $195 to $513Professionalmedian $195 · 10th to 90th $115 to $724
$100$200$500$1Kfacility $347professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$407.38
Typical High
$549.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$151.36
Typical High
$234.42
Cigna
Setting
Professional
Modifier
None
Typical Low
$239.88
Median
$371.54
Typical High
$457.09
Hally Health
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$316.23
Typical High
$707.95
Medica
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$346.74
Typical High
$489.78
Medica
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$234.42
Typical High
$954.99
Midlands
Setting
Professional
Modifier
None
Typical Low
$239.88
Median
$239.88
Typical High
$257.04
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$208.93
Typical High
$407.38
United
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$489.78
United
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$114.82
Typical High
$398.11
Wellmark
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$194.98
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$75.86
Median
$75.86
Typical High
$114.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$30.20
Median
$30.20
Typical High
$46.77

Where Iowa sits

The same service costs 8.3 times more in Texas than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 16th of 51

$204

TX $955DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.