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Analysis Of One Gene

South Carolina rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated October 2026.

How much does Analysis Of One Gene cost?

$195

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $195 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $389 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$135 to $195
FacilityA hospital or hospital-owned outpatient department$389$204 to $741

How much rates vary

Facilitymedian $389 · 10th to 90th $151 to $1,202Professionalmedian $195 · 10th to 90th $93 to $234
$100$200$500$1Kfacility $389professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
Aetna
Setting
Professional
Modifier
None
Typical Low
$151.36
Median
$151.36
Typical High
$154.88
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$269.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$489.78
Typical High
$1,202.26
Cigna
Setting
Professional
Modifier
None
Typical Low
$89.13
Median
$93.33
Typical High
$234.42
Medcost
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$181.97
Typical High
$562.34
Medcost
Setting
Professional
Modifier
None
Typical Low
$154.88
Median
$154.88
Typical High
$269.15
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$234.42
United
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$114.82
Typical High
$194.98
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$75.86
Median
$75.86
Typical High
$77.62
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$30.20
Median
$30.20
Typical High
$30.90
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$77.62
Median
$77.62
Typical High
$154.88

Where South Carolina sits

The same service costs 8.3 times more in Texas than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 21st of 51

$195

TX $955DE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.