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Analysis Of One Gene

Massachusetts rates for HCPCS 81357

A molecular laboratory test that examines the DNA of a single gene from a patient sample and reports the changes it finds. Results are normally reviewed with a specialist who can explain what they mean for the person tested.

Rates data updated July 2026.

How much does Analysis Of One Gene cost?

$195

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $195 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $269 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$155 to $195
FacilityA hospital or hospital-owned outpatient department$269$195 to $562

How much rates vary

Facilitymedian $269 · 10th to 90th $135 to $631Professionalmedian $195 · 10th to 90th $115 to $479
$100$200$500$1K$2K$5Kfacility $269professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$338.84
Typical High
$562.34
Aetna
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$144.54
Typical High
$575.44
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$218.78
Typical High
$630.96
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$194.98
Typical High
$562.34
BCBS
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$181.97
Typical High
$190.55
Cigna
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$151.36
Typical High
$309.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$234.42
Typical High
$416.87
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$281.84
Typical High
$331.13
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$194.98
Typical High
$323.59
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$218.78
Typical High
$630.96
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$194.98
Typical High
$562.34
United
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$194.98
Typical High
$234.42
United
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$194.98
Typical High
$436.52

Where Massachusetts sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 18th of 51

$195

AK $437DE $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.