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Cancer-Related Gene Mutation Test

Nationwide rates for HCPCS 81311

This service is a genetic laboratory test that looks for specific mutations in a gene that is commonly altered in certain cancers. Results can help guide decisions about cancer treatment, including whether a particular targeted therapy is likely to work. The test is run on a tumor tissue sample.

Rates data updated July 2026.

Facilitymedian $468 · 10th–90th $240$1,3180%10%10th90th$468Professionalmedian $251 · 10th–90th $129$5620%10%20%10th90th$251$0.5$5.0$50.0$500.0$5.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$489.78
Typical High
$1,288.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$177.83
Median
$239.88
Typical High
$562.34
BCBS
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$398.11
Typical High
$1,348.96
BCBS
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$162.18
Typical High
$549.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$616.60
Typical High
$1,288.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$331.13
Typical High
$707.95
United
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$295.12
Typical High
$354.81
United
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$177.83
Typical High
$446.68