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Cancer-Related Gene Mutation Test

South Dakota rates for HCPCS 81311

This service is a genetic laboratory test that looks for specific mutations in a gene that is commonly altered in certain cancers. Results can help guide decisions about cancer treatment, including whether a particular targeted therapy is likely to work. The test is run on a tumor tissue sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test cost?

$331

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $331 for this service. The price depends on where it is billed: about $295 from a physician practice, and about $331 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$295$209 to $562
FacilityA hospital or hospital-owned outpatient department$331$331 to $562

How much rates vary

Facilitymedian $331 · 10th to 90th $282 to $562Professionalmedian $295 · 10th to 90th $151 to $708
$200$500$1Kfacility $331professional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$338.84
Aetna
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$275.42
Cigna
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$562.34
Typical High
$562.34
Cigna
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$562.34
Typical High
$707.95
Medica
Setting
Facility
Modifier
None
Typical Low
$281.84
Median
$331.13
Typical High
$346.74
Medica
Setting
Professional
Modifier
None
Typical Low
$151.36
Median
$269.15
Typical High
$537.03
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$446.68
Median
$691.83
Typical High
$812.83
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$177.83
Typical High
$295.12
Wellmark
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$295.12

Where South Dakota sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 14th of 51

$331

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.