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Cancer-Related Gene Mutation Test

Virginia rates for HCPCS 81311

This service is a genetic laboratory test that looks for specific mutations in a gene that is commonly altered in certain cancers. Results can help guide decisions about cancer treatment, including whether a particular targeted therapy is likely to work. The test is run on a tumor tissue sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test cost?

$251

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $251 for this service. The price depends on where it is billed: about $224 from a physician practice, and about $380 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$224$166 to $295
FacilityA hospital or hospital-owned outpatient department$380$295 to $692

How much rates vary

Facilitymedian $380 · 10th to 90th $295 to $1,445Professionalmedian $224 · 10th to 90th $123 to $427
$100$200$500$1K$2K$5K$10Kfacility $380professional $224

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$251.19
Typical High
$691.83
Aetna
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$223.87
Typical High
$251.19
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$1,445.44
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$158.49
Typical High
$213.80
CareFirst
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$234.42
Typical High
$295.12
Cigna
Setting
Facility
Modifier
None
Typical Low
$302.00
Median
$575.44
Typical High
$1,000.00
Cigna
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$181.97
Typical High
$467.74
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$281.84
Median
$323.59
Typical High
$416.87
Medcost
Setting
Facility
Modifier
None
Typical Low
$398.11
Median
$398.11
Typical High
$537.03
Medcost
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$190.55
Typical High
$295.12
Sentara
Setting
Facility
Modifier
None
Typical Low
$218.78
Median
$380.19
Typical High
$10,232.93
Sentara
Setting
Professional
Modifier
None
Typical Low
$269.15
Median
$346.74
Typical High
$1,288.25
United
Setting
Facility
Modifier
None
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$177.83
Typical High
$407.38
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$112.20
Median
$112.20
Typical High
$125.89
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$44.67
Median
$44.67
Typical High
$50.12

Where Virginia sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 35th of 51

$251

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.