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Cancer-Related Gene Mutation Test

Indiana rates for HCPCS 81311

This service is a genetic laboratory test that looks for specific mutations in a gene that is commonly altered in certain cancers. Results can help guide decisions about cancer treatment, including whether a particular targeted therapy is likely to work. The test is run on a tumor tissue sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test cost?

$234

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $234 for this service. The price depends on where it is billed: about $178 from a physician practice, and about $295 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$178$117 to $295
FacilityA hospital or hospital-owned outpatient department$295$269 to $646

How much rates vary

Facilitymedian $295 · 10th to 90th $234 to $891Professionalmedian $178 · 10th to 90th $117 to $447
$200$500$1K$2Kfacility $295professional $178

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$446.68
Typical High
$1,096.48
Aetna
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$239.88
Typical High
$446.68
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$295.12
Typical High
$891.25
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$117.49
Typical High
$446.68
CareSource
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$323.59
Typical High
$416.87
Cigna
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$295.12
Typical High
$831.76
Cigna
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$269.15
Typical High
$562.34
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$741.31
Typical High
$2,187.76
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$251.19
Typical High
$457.09
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$177.83
Typical High
$354.81
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$112.20
Median
$120.23
Typical High
$223.87
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$44.67
Median
$48.98
Typical High
$89.13

Where Indiana sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 39th of 51

$234

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.