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Cancer-Related Gene Mutation Test

Iowa rates for HCPCS 81311

This service is a genetic laboratory test that looks for specific mutations in a gene that is commonly altered in certain cancers. Results can help guide decisions about cancer treatment, including whether a particular targeted therapy is likely to work. The test is run on a tumor tissue sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test cost?

$324

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $324 for this service. The price depends on where it is billed: about $302 from a physician practice, and about $380 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$302$178 to $562
FacilityA hospital or hospital-owned outpatient department$380$295 to $603

How much rates vary

Facilitymedian $380 · 10th to 90th $288 to $759Professionalmedian $302 · 10th to 90th $178 to $977
$200$500$1Kfacility $380professional $302

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$616.60
Typical High
$831.76
Aetna
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$229.09
Typical High
$354.81
Cigna
Setting
Professional
Modifier
None
Typical Low
$363.08
Median
$562.34
Typical High
$707.95
Hally Health
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$489.78
Typical High
$851.14
Medica
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$380.19
Typical High
$660.69
Medica
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$354.81
Typical High
$1,479.11
Midlands
Setting
Professional
Modifier
None
Typical Low
$363.08
Median
$363.08
Typical High
$389.05
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$323.59
Typical High
$630.96
United
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$758.58
United
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$177.83
Typical High
$602.56
Wellmark
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$295.12
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$114.82
Median
$114.82
Typical High
$177.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$45.71
Median
$45.71
Typical High
$70.79

Where Iowa sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 15th of 51

$324

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.