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Cancer-Related Gene Mutation Test

Missouri rates for HCPCS 81311

This service is a genetic laboratory test that looks for specific mutations in a gene that is commonly altered in certain cancers. Results can help guide decisions about cancer treatment, including whether a particular targeted therapy is likely to work. The test is run on a tumor tissue sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test cost?

$295

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $295 for this service. The price depends on where it is billed: about $282 from a physician practice, and about $513 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$282$178 to $479
FacilityA hospital or hospital-owned outpatient department$513$324 to $813

How much rates vary

Facilitymedian $513 · 10th to 90th $269 to $1,413Professionalmedian $282 · 10th to 90th $148 to $741
$200$500$1K$2Kfacility $513professional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$380.19
Typical High
$549.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$257.04
Typical High
$338.84
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$1,380.38
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$309.03
Typical High
$691.83
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$407.38
Median
$426.58
Typical High
$812.83
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$295.12
Typical High
$562.34
Cigna
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$660.69
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$229.09
Typical High
$380.19
Medica
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$436.52
Typical High
$1,412.54
Medica
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$309.03
Typical High
$1,479.11
United
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$269.15
Typical High
$269.15
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$177.83
Typical High
$398.11
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$125.89
Median
$125.89
Typical High
$169.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$50.12
Median
$51.29
Typical High
$67.61

Where Missouri sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 23rd of 51

$295

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.