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Cancer-Related Gene Mutation Test

Missouri rates for HCPCS 81311

This service is a genetic laboratory test that looks for specific mutations in a gene that is commonly altered in certain cancers. Results can help guide decisions about cancer treatment, including whether a particular targeted therapy is likely to work. The test is run on a tumor tissue sample.

Rates data updated July 2026.

How much does Cancer-Related Gene Mutation Test cost?

$288

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $288 for this service. The price depends on where it is billed: about $257 from a physician practice, and about $389 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$257$170 to $347
FacilityA hospital or hospital-owned outpatient department$389$295 to $513

How much rates vary

Facilitymedian $389 · 10th to 90th $275 to $692Professionalmedian $257 · 10th to 90th $117 to $575
$200$500$1Kfacility $389professional $257

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$501.19
Typical High
$691.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$257.04
Typical High
$588.84
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$295.12
Typical High
$1,047.13
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$181.97
Typical High
$512.86
BCBS
Setting
Facility
Modifier
Global
Typical Low
$407.38
Median
$426.58
Typical High
$776.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$295.12
Typical High
$501.19
Cigna
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$616.60
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$151.36
Typical High
$398.11
Medica
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$371.54
Typical High
$1,412.54
Medica
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$177.83
Typical High
$1,479.11
United
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$295.12
Typical High
$354.81
United
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$177.83
Typical High
$398.11

Where Missouri sits

The same service costs 3.3 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 28th of 51

$288

AK $661DE $200

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.